The consumption of an astounding one million acres resulted in California’s largest single fire to date, the 2021 Dixie Fire. The social and economic losses associated with the fire were immediately apparent, but the effects on wildlife remained unknown. While previous research has suggested mixed or low severity fire may be beneficial to certain wildlife species, the responses to megafires are poorly understood for many carnivores. To better understand these responses to severe fire, we used a random sampling design stratified by burn severity to survey in and around the Dixie Fire footprint using baited camera stations. This allowed us to determine the occurrence of mesocarnivores including Pacific marten (Martes caurina) and fisher (Pekania pennanti) in a post-fire landscape. We estimated occupancy at multiple scales using forest structure metrics related to burn severity, basal area, and prey availability. Our results provide insight into whether and how mesocarnivores adapt to high severity fires. We equip land managers with applicable information for restoration and future conservation of forest-obligate species.