For decades translocation has been under-utilized as a tool mountain lion (Puma concolor) management because limited prior research showed low survival and homing behavior in translocated individuals. Lethal removal of mountain lions can reduce predation on endangered species and mitigate human-wildlife conflict, but legislation or public opposition may require non-lethal management strategies in some jurisdictions. We translocated 21 mountain lions between 2020 and 2025 for the protection of federally endangered Sierra Nevada bighorn sheep (Ovis canadensis sierrae) and documented statistically similar annual survival rates between translocated and non-translocated mountain lions within our study area. Homing behavior was uncommon and was only documented in 2 adult males. Our results the feasibility of mountain lion translocations as a management strategy with implications for predation management, human-wildlife conflict mitigation, and genetic augmentation efforts for endangered mountain lion populations.